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Sissy M Jhiang Selected Research

Iodides

2/2018The rs2910164 Genetic Variant of miR-146a-3p Is Associated with Increased Overall Mortality in Patients with Follicular Variant Papillary Thyroid Carcinoma.
10/2015Modulation of thyroidal radioiodide uptake by oncological pipeline inhibitors and Apigenin.
8/2013Modulation of sodium/iodide symporter expression in the salivary gland.
4/2013MEK inhibition leads to lysosome-mediated Na+/I- symporter protein degradation in human breast cancer cells.
6/2012Modulation of sodium iodide symporter expression and function by LY294002, Akti-1/2 and Rapamycin in thyroid cells.
10/2011Microarray analysis of genes associated with cell surface NIS protein levels in breast cancer.
2/2011Single photon emission computed tomography imaging for temporal dynamics of thyroidal and salivary radionuclide accumulation in 17-allyamino-17-demothoxygeldanamycin-treated thyroid cancer mouse model.
12/2007Identification of in vivo phosphorylation sites and their functional significance in the sodium iodide symporter.
7/2007PI3K activation is associated with intracellular sodium/iodide symporter protein expression in breast cancer.
6/2007MEK signaling modulates sodium iodide symporter at multiple levels and in a paradoxical manner.
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Sissy M Jhiang Research Topics

Disease

28Thyroid Neoplasms (Thyroid Cancer)
01/2021 - 02/2002
17Neoplasms (Cancer)
02/2018 - 02/2002
5Breast Neoplasms (Breast Cancer)
02/2015 - 10/2004
3Papillary Thyroid Cancer
06/2007 - 09/2003
2Carcinogenesis
01/2006 - 06/2003
2Lacrimal Duct Obstruction
09/2005 - 12/2002
1Renal Cell Carcinoma (Grawitz Tumor)
11/2017
1Pheochromocytoma
11/2017
1Glioblastoma (Glioblastoma Multiforme)
11/2017
1Sialadenitis
11/2016
1Xerostomia
11/2016
1Neoplasm Metastasis (Metastasis)
04/2013
1Adenoma (Adenomas)
01/2006
1Carcinoma (Carcinomatosis)
01/2006
1Fibrosis (Cirrhosis)
09/2005
1Multiple Hamartoma Syndrome (Cowden's Disease)
06/2003
1Anaplastic Thyroid Carcinoma
06/2003
1Follicular Adenocarcinoma
06/2003
1Lacrimal Apparatus Diseases (Epiphora)
12/2002
1Prostatic Neoplasms (Prostate Cancer)
02/2002
1Lymphatic Metastasis
02/2002

Drug/Important Bio-Agent (IBA)

13sodium-iodide symporter (sodium iodide symporter)IBA
02/2018 - 02/2002
13IodidesIBA
02/2018 - 02/2002
10SymportersIBA
01/2021 - 05/2004
8IodineIBA
01/2021 - 12/2002
6Radioisotopes (Radionuclides)IBA
04/2013 - 02/2002
3Thyrotropin (Thyroid-Stimulating Hormone)FDA Link
10/2015 - 05/2014
3Messenger RNA (mRNA)IBA
02/2015 - 10/2004
3RacivirIBA
01/2006 - 06/2003
2DNA (Deoxyribonucleic Acid)IBA
02/2018 - 01/2006
2ApigeninIBA
10/2015 - 05/2014
2Hydrocortisone (Cortisol)FDA LinkGeneric
02/2015 - 04/2013
2Indicators and Reagents (Reagents)IBA
12/2014 - 05/2014
2Mitogen-Activated Protein Kinase Kinases (MEKs)IBA
04/2013 - 06/2007
1Succinate Dehydrogenase (Fumarate Reductase)IBA
11/2017
1EnzymesIBA
11/2017
1CytokinesIBA
10/2015
1FlavonoidsIBA
10/2015
12- (1H- indazol- 4- yl)- 6- (4- methanesulfonylpiperazin- 1- ylmethyl)- 4- morpholin- 4- ylthieno(3,2- d)pyrimidineIBA
10/2015
1AcidsIBA
02/2015
1MAP Kinase Kinase Kinases (MAP Kinase Kinase Kinase)IBA
04/2013
1Tretinoin (Retinoic Acid)FDA LinkGeneric
04/2013
1Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA
04/2013
1Mechanistic Target of Rapamycin Complex 1IBA
06/2012
1cysteinyl-tRNA synthetaseIBA
10/2011
1OligonucleotidesIBA
10/2011
1Biomarkers (Surrogate Marker)IBA
10/2011
1Small Interfering RNA (siRNA)IBA
10/2010
1Proteins (Proteins, Gene)FDA Link
07/2007
1Membrane Glycoproteins (Membrane Glycoprotein)IBA
07/2007
1Mitogen-Activated Protein KinasesIBA
06/2007
1Lysine (L-Lysine)FDA Link
09/2005
1IntegrinsIBA
09/2005
1Coxsackie and Adenovirus Receptor-Like Membrane ProteinIBA
09/2005
1tanespimycin (17AAG)IBA
10/2004
1Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
10/2004
1Phosphotransferases (Kinase)IBA
10/2004
1Adenosine Monophosphate (AMP)IBA
10/2004
1IsotopesIBA
02/2004
1Dextrans (Dextran)FDA Link
09/2003
1Protein Isoforms (Isoforms)IBA
09/2003
1Bone Morphogenetic Proteins (Bone Morphogenetic Protein)IBA
06/2003
1Caveolin 1IBA
06/2003
1Phenylalanine (L-Phenylalanine)FDA Link
11/2002
1Tyrosine (L-Tyrosine)FDA Link
11/2002

Therapy/Procedure

17Therapeutics
01/2021 - 02/2002
1Thyroidectomy
11/2017
1Dacryocystorhinostomy
09/2005
1Prostatectomy (Retropubic Prostatectomy)
02/2002